Ketacon
Ketoconazole is used to treat skin infections such as athlete’s foot, jock itch, ringworm, and certain kinds of dandruff. Ketoconazole is also indicated in treatment of pityriasis(tinea versicolor), a fungal infection causes a lightening or darkening of skin of the neck, chest, arms, or legs.
Mode of Action: In vitro studies suggest that ketoconazole impairs the synthesis of ergosterol, which is a vital component of fungal cell membranes.
Microbiology: Ketoconazole is a broad spectrum synthetic antifungal agent which inhibits the in vitro growth of the following common dermatophytes and yeasts by altering the permeability of the cell membrane: Dermatephytes Trichophyton rubrum, T. mentagrophytes, T. tonsurans, Microsporum cam’s, M. audouini. M. gypseum and Epidermophyton floc-cosum; yeasts: candida albicans, Malassezia ovale (Pityrosporum ovale) and C. Tropicalis; and the organism responsible for tinea versicolor, Malassezia. furfur (Pityrosporum orbiculare).
Cutaneous candidiasis, tinea corporis, tinea cruris, tinea pedis, and tinea (pityriasis) versicolor: it is recommended that ketoconazole cream, 2% be applied once daily to cover the affected area and immediate surrounding area. Clinical imprc :ement may be seen fairly soon after treatment is begun; however, candidal infections and tinea cruris and corporis should be treated for two weeks in other to reduce the possibility of recurrence. Patients with tinea versicolor usually require two weeks of treatment. Patients with Tinea pedis require six weeks of treatment.
Ketoconazole cream, 2% is contraindicated in persons who have shown hypersensitivity to the active or excipient ingredients of this formulation.
If a reaction suggesting sensitivity or chemical irritation should occur, use of the medication should be discontinued.
Nursing Mothers: It is not known whether Ketoconazoie cream, 2% administered topically could result in sufficient systemic absorption to produce detectable quantities in breast milk.
Pediatric Use: Safety and effectiveness in children have not been established Ketoconazole cream, 2% is contraindicated in persons who have shown. Hypersensitivity to the active or excipient ingredients of this formulation.
Severe irritation, pruritus and stinging.
Ketoconazole cream, 2% is not for ophthalmic use.
Store below 30°C, protected from light.
12*30gm Tube
A4-5364
6154000136130